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Posted May 5, 2026

Senior Machine Learning Engineer

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Paradigm is rebuilding the clinical research ecosystem by enabling equitable access to trials for all patients. Our platform enhances trial efficiency and reduces the barriers to participation for healthcare providers. Incubated by ARCH Venture Partners and backed by leading healthcare and life sciences investors, Paradigm’s seamless infrastructure implemented at healthcare provider organizations, will bring potentially life-saving therapies to patients faster.

Our team hails from a broad range of disciplines and is committed to the company’s mission to create equitable access to clinical trials for any patient, anywhere. Join us, and bring your expertise, passion, creativity, and drive as we work together to realize this mission.

As a Senior Machine Learning Engineer, you will take a leading role in designing and deploying sophisticated ML models, including GenAI and LLM-based solutions, that optimize clinical trial workflows and patient engagement. This position offers an opportunity to impact healthcare by developing state-of-the-art models that enhance trial design, accelerate patient recruitment, and improve overall trial efficiency. You will contribute to both high-level architecture decisions and hands-on implementation, driving the technology forward and influencing ML strategies across Paradigm.

Responsibilities:

Qualifications:

Preferred:

What You’ll Receive:
Paradigm Health offers a comprehensive Total Rewards package to support your well-being and success, including:
  • Competitive health, dental, and vision insurance
  • Mental health support for you and your family through Spring Health
  • Equity package
  • Unlimited paid time off (PTO)
  • 16 weeks of paid parental leave
  • Flexible work options – remote and hybrid arrangements
  • Company-paid life insurance
  • Company-paid short-term and long-term disability coverage
  • One Medical membership
  • 401(k) plan with company match

At Paradigm, we are committed to providing equal employment opportunities to all qualified individuals. We encourage and welcome candidates from all backgrounds and perspectives to apply for our open positions. We are interested in all qualified individuals and  ensure that all employment decisions are based on job-related factors such as skills, experience, and qualifications.

Interested in this role?Apply on iHire