M365/Azure Principal Systems Engineer - Remote

At Prime Therapeutics (Prime), we are a different kind of PBM, with a purpose beyond profits and a unique ability to connect care for those we serve. Looking for a purpose‑driven career? Come build the future of pharmacy with us.
M365/Azure Principal Systems Engineer - Remote Job Description

We are seeking a Principal Systems Engineer specializing in Microsoft 365 and Azure to join our Enterprise Technology Transformation and Operations team. If you enjoy being an influencer, shaping strategic direction, and driving innovation across enterprise technology, this role may be exactly what you’ve been looking for. In this position, you will serve as the product representative and strategic thought leader for our M365 and Azure ecosystem. You’ll collaborate with technology and business stakeholders to define and advance the strategy, roadmap, and architectural vision for Microsoft cloud solutions across the organization.
Responsibilities Represent broad expertise in domain team in technical design and estimating sessions with internal and external IT customers Provide support for and create logical and physical design Analyze and recommend changes to improve efficiency, lower costs, and enhance quality of business applications Establish design patterns used within domain Serve as thought leader and final decision maker in driving teams to conclusions regarding technical solutions Other duties as assigned Minimum Qualifications Bachelor's degree in computer science or related area of study, or equivalent combination of education and/or relevant work experience; High School Diploma or GED equivalent required 7 years of technical experience in a variety of infrastructure areas M365 Service Azure Must be eligible to work in the United States without need for work visa or residency sponsorship Additional Qualifications The ability to understand how M365, Azure and architecture work together. Excellent written, technical, and verbal communication skills Ability and drive to excel in a growing, changing, and collaborative environment Established presenter of technical and non‑technical material adapted to the respective audience Ability to transition abstract concepts into technical deployment designs Ability to develop decision criteria and develop unbiased technology comparisons Strong problem‑solving and business analysis skills Preferred Qualifications Master's degree in Computer Engineering ITIL Foundation Certification Experience working in environment with regulatory compliance requirements (HIPAA, PCI, etc.) Previous experience in PBM / health care industry Broad experience in the infrastructure domain working with IT Architecture Understanding of security implications of domain

Potential pay for this position ranges from $108,000.00 - $184,000.00 based on experience and skills.

To review our Benefits, Incentives and Additional Compensation, visit our Benefits Page and click on the "Benefits at a glance" button for more detail (

Prime Therapeutics LLC is proud to be an equal opportunity and affirmative action employer. We encourage diverse candidates to apply, and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sex (including pregnancy), national origin, disability, age, veteran status, or any other legally protected class under federal, state, or local law. We welcome people of different backgrounds, experiences, abilities, and perspectives including qualified applicants with arrest and conviction records and any qualified applicants requiring reasonable accommodations in accordance with the law.

Prime Therapeutics LLC is a Tobacco‑Free Workplace employer.

If you are an applicant with a disability and need a reasonable accommodation for any part of the employment process, please contact Human Resources at or email

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